Metabolism peceded the formation of molecules

Metabolism reactions on earth preseded the formation of information molecules such RNA.
user1 ·
2017-03-17 12:14:58
test comments 1
user1 ·
2017-03-17 12:15:02
test comments 2
user1 ·
2017-03-21 06:26:51
dsadsa
vs.

Information molecules preceded metabolism

Information molecules such as RNA came about earlier than networks of metabolic reactions, which might have been catalyzed by short proteins.
Curator:
curator2      

Background

test category

ARG

A series of prebiotic reactions and energy sources might have led to the emergence of metabolism in hydrothermal vents.

ARG

Spontaneous emergence of the reverse (reductive) citic acid cycle and other autocatalytic cycles was highly implausible.

user1 ·
2017-03-18 23:12:50
comment
user1 ·
2017-03-21 04:57:24
comment II

Formation of non-enzymatic, small molecule metabolism is possible

user1 ·
2017-03-17 12:15:16
test comments argument 1
user1 ·
2017-03-18 18:46:33
test 2
ARG

Reductive tricarboxylic acid (TCA) cycle was a primordial, autocatalytic cycle.

eEvidence test1
cCitation
The Gold King Mine spill in August 2015 released 11 million liters of metal-rich mine waste to the Animas River watershed, an area that has been previously exposed to historical mining activity spanning more than a century. Although adsorption onto fluvial sediments was responsible for rapid immobilization of a significant fraction of the spill-associated metals, patterns of longer-term mobility are poorly constrained. Metals associated with river sediments collected downstream of the Gold King Mine in August 2015 exhibited distinct presence and abundance patterns linked to location and mineralogy. Simulating riverbed burial and development of anoxic conditions, sediment microcosm experiments amended with Animas River dissolved organic carbon revealed the release of specific metal pools coupled to microbial Fe- and SO4(2-)-reduction. Results suggest that future sedimentation and burial of riverbed materials may drive longer-term changes in patterns of metal remobilization linked to anaerobic microbial metabolism, potentially driving decreases in downstream water quality. Such patterns emphasize the need for long-term water monitoring efforts in metal-impacted watersheds.

ARG

Spontaneous emergence of the reverse (reductive) citic acid cycle and other autocatalytic cycles was highly implausible.

eEvidence Cumulative advantages
cCitation
The big problem in global public health, arising from the international migration of physicians from less-developed to more-developed countries, increases if this migration also affects scientists dedicated to health areas. This article analyzes critical variables in the processes of Spanish scientific mobility in Health Sciences to articulate effective management policies for the benefit of national public health services and the balance between local and global science.